Cholesterol is waxy, fat-like substance found in the walls of cells in all parts of the body. The body also uses cholesterol to make hormones, bile acids, vitamin D, and other substances.
Cholesterol comes from diet and also the body makes the cholesterol needed. As Cholesterol is not water-soluble, it circulates in the bloodstream in packages called lipoproteins, which have fat (lipid) inside and protein outside.

Two main kinds of lipoproteins carry cholesterol in the blood:

If there is too much bad cholesterol in the blood, some of it becomes trapped in the artery walls. Over time, this builds up and is called plaque. The plaque can narrow vessels and make them less flexible, a condition called atherosclerosis or “hardening of the arteries”. This process can happen to blood vessels anywhere in the body. When atherosclerosis affects the blood vessels supplying the heart leading to their narrowing, it is called coronary artery disease. When these plaques become unstable as some of them do, they produce sudden occlusion of the blood vessel supplying the heart leading to the condition called a heart attack.

Factors that affect cholesterol levels in the blood:

Cholesterol level in blood can be lowered by:

Therapeutic lifestlye changes :


Become Physically Active:

Maintaining a healthy weight:


Various medicines are now available for managing the lipid levels in the blood like statins, fibrates, niacin, Omega 3 fatty acids, ezetimibe etc. Of them, Statins are the most important ones with a proven mortality benefit in primary and secondary prevention of coronary artery disease. They may be prescribed to you by your physician or cardiologist as appropriate depending on your lipid profile report and your risk factor level.

High Triglycerides:

Causes of raised triglycerides are overweight/obesity, physical inactivity, cigarette smoking, excess alcohol intake, and diet very high in carbohydrates (60 percent of calories or higher). To reduce blood triglyceride levels: control your weight, be physically active, don’t smoke, limit alcohol intake, and limit simple sugars and sugar-sweetened beverages. Sometimes, medication also is needed.

Target lipid levels:

LDL cholesterol: Less than 100 mg/dl (less than 70 mg/dl in CAD pts)
HDL cholesterol: More than 40 mg/dl in males and more than 50 mg/dl in females.
Triglycerides : Less than 150 mg/dl

Please follow and like us:

Leave a Reply

Your email address will not be published. Required fields are marked *